Liposomes have a long history in the study of biological membranes. More recently, liposomes have been evaluated as delivery systems for drugs, vitamins and cosmetic materials. Liposomes can be custom designed for almost any need by varying the lipid content, size, surface charge and method of preparation. The preparation of liposomes requires careful attention to ease of formulation, encapsulation efficiency and production capacity.

Research into the use of liposomes for topical skin application was pioneered by Prof. Michael Mezei and his group in the early 1980's.1994 Prof.Mezie started the first studies using Minoxidil encapsulated in liposomes.The liposome wall is very similar, physiologically, to the material of cell membranes. When a Minoxidil solution entrapped in liposomes is applied to the skin, for example, the Minoxidil liposomes are deposited on the skin and begin to merge with the cellular membranes. In the process, the liposomes release their payload of active materials into the cells. As a consequence, not only is delivery of the actives very specific--directly into the intended cells--but the delivery takes place over a longer period of time. Minoxidil  ingredients in liposomes exhibit better stability, penetration and efficacy at lower usage levels.

Starting fall of 2004 some of our products will use nanosomes. Nanosomes are multilayered very small liposomes with a especially rigid shell. The nanosome is used in particular to transport lipophilic active ingredients, that is those that are soluble in oil. Given that the interstices of the outer layer of skin measure about 100 nanometers, nanosomes offer the best solution to the problem of transporting and concentrating active ingredients in the skin.